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The Pancreatic Cancer Database is a resource of experimentally demonstrated molecular alterations associated with pancreatic cancer in cancer tissues or cancer cell lines. It currently contains information pertaining to changes at the mRNA, protein and miRNA levels. The data can be queried or browsed at mRNA, protein or miRNA levels or based on specific cancer subtypes. Individual entries are also linked to Entrez Gene, OMIM, Human Protein Reference Database (HPRD), HGNC and miRBase.
Statistics
RNA alterations
8,489
Protein alterations
2,882
miRNA alterations
744
PubMed links
12,085
Last updated
July 4, 2015
Gene symbol
Protein name
PubMed
Accession
select database
HPRD
OMIM
Swiss-Prot
HGNC
Molecular alterations
select
miRNA Expression
Protein Expression
RNA Expression
Cancer/Disease types
select
Adenosquamous carcinoma
Chronic Pancreatitis
Endocrine neoplasms
Insulinoma
Intraductal papillary mucinous neoplasms
Invasive ductal adenocarcinoma
Mucinous cystic neoplasms
Ductal adenocarcinoma
Pancreatic intraepithelial neoplasia (PanIN)
Cell lines
select
A818-1
A8184
A818-6
AsPC-1
BxPC-3
Capan-1
Capan-2
CFPAC-1
Colo-357
Colo357L3.6pl
Dan-G
E3LZ10.7
FA6
GM6L
GS2.1
H48N
HCG-25
HPAC
HPAF/CD18
HPAF-II
HPARF-11
HPDE
Hs 700T
Hs 766T
HUP-T3
HUP-T4
IMIM-PC-l
IMM-PC2
JD13A
KLM
KLM-1
KP-1N
KP-2
KP-3
L3.3
L3.6pl
MDAPanc3
MIA PaCa-2
MPanc-96
NOR-P1
PaCa-2
PaCa-3
PaCa-44
PAN-03-JCK
PAN-07-JCK
PAN-08-JCK
PAN-09-JCK. T
Panc-04.03
PANC-1
Panc-10.05
Panc-2.03
Panc-28
Panc-3
Panc-3.27
Panc-4.30
Panc-48
Panc-8.13
Panc-89
PancTu1
PA-TU 8988S
PA-TU 8988T
PC-13
PCI-19
PCI-24
PCI-55
PCI-64
PCI-66
PDEC
PK-1
PK-45H
PK-45P
PK-59
PK-8
PK-9
PL-1
PL-12
PL-13
PL-3
PL-4
PL-45
PL-5
PL-8
PL-9
PSN-1
PT45
PT-45
PT45P1
QGP1
RWP-1
SK-PC-3
SK-PC-l
SU.86.86
SUIT 007
SUIT 028
SUIT-2
SW1990
SW850
SW979
T3M4
XPA-1
XPA-3
XPA-4
Experimental methods
select
Array-based sandwich assay
Bio-plex cytokine assay
cDNA microarray
DNA microarray
Differential gel electrophoresis (DIGE)
Enzyme immunoassay
ELISA
Flow cytometry
Fluorescence activated cell sorting (FACS)
In situ hybridization
Immunoblot
Immunohistochemistry
Isobaric tags for relative and absolute quantitation (iTRAQ)
Isotope coded affinity tagging (ICAT)
Multiple proximity ligation assay
miRNA array
Northern blot
Protein microarray
qRT-PCR
RT-PCR
Surface enhanced laser desorption and ionization (SELDI)
Serialanalysis of gene expression (SAGE)
Stable isotope labeling with amino acids in cell culture (SILAC)
Tandem mass spectrometry
Two dimensional gel electrophoresis (2-DE)
Western blot
Please cite the following references:
Harsha, H. C. et al. (2009). A compendium of potential biomarkers of pancreatic cancer.
PLoS Medicine
. 6, e1000046. [
PubMed
]
Thomas, J. K. et al. (2014). Pancreatic Cancer Database: An integrative resource for pancreatic cancer.
Cancer Biology and Therapy
. 15, 8. [
PubMed
]