Director
Publications
Molecular Biology Lab
Proteomics
Metabolomics
Infractructure
Phd
funding
Collaborators
visitors gallery
Trainees

 
Harsh Pawar, Ph.D.
Faculty Scientist
 
Institute of Bioinformatics
Discoverer Building, International Tech Park, Whitefield
Bangalore - 560 066
E-mail: harsh at ibioinformatics dot org
Phone: +91-80-68982140 2140
 
Education
Ph.D. in Pathology, Rajiv Gandhi University of Health Sciences, Bangalore, India, 2014
M.Sc. in Zoology, University of Pune, Pune, India, 2006
 

Positions Held

Faculty Scientist, Institute of Bioinformatics, Bangalore, October 2024-present
Visiting Researcher, Biomedical and Life Science Division, Lancaster University, Lancaster, United Kingdom, April 2024-September 2024 
Senior Research Associate (SRA), Biomedical and Life Science Division, Lancaster University, Lancaster, United Kingdom, December 2020-March 2024 
Israel Planning and Budgeting Committee (PBC) Postdoctoral Fellow, Faculty of Biology, Technion- Israel Institute of Technology, Haifa, Israel, July 2016 - December 2020
University Grants Commission (UGC) Dr. D. S. Kothari Postdoctoral Fellow, Department of Zoology, Savitribai Phule Pune University, February 2015 - June 2016 
Senior Research Fellow, Institute of Bioinformatics, Bangalore, India, 2011 - 2014 
Junior Research Fellow, Institute of Bioinformatics, Bangalore, India, 2008 - 2010 
 

Area of Specialization

Insect vector biology
Kinetoplastid protozoan biology and Parasitology
Pathogen nutrient sensing and uptake
Phosphoproteomics and nutrient signalling
Proteogenomics and genome annotations
Cancer biomarker discovery
Proteomics, Genomics
 
 

Publications

Research papers: 28

Munjal, N., Dey, G., Parthasarathi, S., Chauhan, K., Pai, K., Patole, M.S., Pawar, H., Sharma, J. (2025). A proteogenomic approach for the identification of virulence factors in Leishmania parasites.. Methods in Molecular Biology- Proteogenomics. 2859(NA):279-96. [PubMed]

Patole, M.S., Sharma J., Pawar, H. (2025). Comparative Proteogenomic Approaches for Mapping the Global Proteome of the Unsequenced Leishmania Vector Phlebotomus papatasi. Methods in Molecular Biology- Proteogenomics. 2859(NA):265-77. [PubMed]

Madan, E., Ganguly, N.K., Puri, M., Pawar, H., Selvapandiyan, A.; Muthuswami, R., Zilberstein, D., Madhubala, R. (2024). Leishmania parasite arginine deprivation response pathway influences the host macrophage lysosomal arginine sensing machinery.. Medical Research Archives. 12(10):001-13. [PubMed]

Routaray, C.B., Kumar, A., Sundar, S., Sathe, G., Pawar, H.*, Pai, K.* (2022). An In-depth Proteomic Map of Leishmania donovani Isolate from Post Kala-azar Dermal Leishmaniasis (PKDL) Patient. Acta Parasitologica. 67(2):687-696. [PubMed]

Goldman, P.A., Kannan, S., Koren, R.N., Puri, M., Pawar, H., Avraham, Y.B., McDonald, J., Sur, A., Zhang, W., Matlashewski, G., Madhubala, R., Michaeli, S., Myler, P.J. and Zilberstein, D. (2020). Sensing host arginine is essential for Leishmania parasites' intracellular development.. Mbio. 11(5):001-13. [PubMed]

Pawar, H., Sathe, G., Patole, M.S. (2020). Genome-Wide Proteomics and Phosphoproteomics Analysis of Leishmania spp. During Differentiation. Methods in Molecular Biology- Trypanosomatids. 2116(NA):161-76. [PubMed]

Pawar, H., Puri, M., Fischer, W.R., Madhubala, R., Zilberstein, D. (2019). The arginine sensing and transport binding sites are distinct in the human pathogen Leishmania.. PLOS Neglected Tropical Diseases. 13(4):001-22. [PubMed]

Tungekar, A., Mandarthi, S., Mandaviya, P.R., Gadekar, V.P., Tantry, A., Kotian, S., Reddy, J., Prabha, D., Bhat, S., Sahay, S., Mascarenhas, R., Badkillaya, R.R., Nagasampige, M.K., Yelnadu, M., Pawar, H., Hebbar, P., Kashyap, M.K. (2018). ESCC ATLAS: A population wide compendium of biomarkers for Esophageal Squamous Cell Carcinoma. Scientific Reports. 8(1):001-15. [PubMed]

Pawar, H.*, Pai, K., Patole, M.S. (2017). A novel protein coding potential of long intergenic non-coding RNAs (lincRNAs) in the kinetoplastid protozoan parasite Leishmania major. . Acta Tropica. 167(NA):21-25. [PubMed]

Pawar, H., Srikanth, S.M., Kashyap, M.K., Sathe, G., Chavan, S., Singal, M., Manju, H.C., Kumar, K.V., Vijayakumar, M., Sirdeshmukh, R., Pandey, A., Prasad, T.S., Gowda, H., Kumar, R.V. (2015). Downregulation of S100 Calcium Binding Protein A9 in Esophageal Squamous Cell Carcinoma.. Scientific World Journal. . 325721(152):001-10. [PubMed]

Pawar, H., Chavan, S., Mahale, K., Khobragade, S., Kulkarni, A., Patil, A., Chaphekar, D., Varriar, P., Sudeep, A., Pai, K., Prasad, T.S., Gowda, H., Patole, M.S. (2015). A proteomic map of the unsequenced kala-azar vector Phlebotomus papatasi using cell line. Acta Tropica. 152(NA):80-89. [PubMed]

Jamdhade, M.*, Pawar, H.*, Chavan, S., Sathe, G., Mahale, K.N., Kulkarni, A., Dixit, T., Madugundu, A. K., Prasad, T.S.K., Harsha, H.C., Pandey, A. and Patole, M.S. (2015). Comprehensive proteomic analysis of glycosomes from Leishmania donovani.. OMICS: A Journal of Integrative Biology. 19(3):157-70. [PubMed]

Pawar, H., Kulkarni, A., Dixit, T., Chaphekar, D. and Patole, M.S. (2014). A bioinformatics approach to reanalyze the genome annotation of kinetoplastid protozoan parasite Leishmania donovani. Genomics. 104(6 Pt B):554-61. [PubMed]

Pawar, H., Renuse S., Khobragade S.N., Chavan, S., Sathe, G., Kumar, P., Mahale, K.N., Gore, K., Kulkarni, A., Dixit, T., Raju, R., Prasad, T.S.K., Harsha, H.C., Patole, M.S. and Pandey, A.(Neglected tropical diseases and omics science: proteogenomics analysis of the promastigote stage of Leishmania major parasite). 2014. OMICS: A Journal of Integrative Biology. In press.

Soni, B.L., Marimuthu, A., Pawar, H., Sawant, S. S., Borges A., Kannan, R., Pandey, A., Ingle, A. D., Harsha, H. C., Vaidya, M. M. (2014). Quantitative proteomic analysis of different stages of rat lingual carcinogenesis.. Clinical Communications-Oncology. 12(NA):001-13. [PubMed]

Sekhar, N.R.*, Pawar, H.*, Renuse, S.*, Kumar, P., Chavan, S., Sathe, G., Sharma, J., Khobragade, S. N., Pande, J., Modak, B., Prasad, T.S.K., Harsha, H.C., Milind S. Patole, M.S. and Pandey, A. (2014). Moving from unsequenced to sequenced genome: reanalysis of the proteome of Leishmania donovani. Proteomics. 97(NA):48-61. [PubMed]

Venugopal, A.K., Ghantasala, S.S., Selvan, L.D., Mahadevan, A., Renuse, S., Kumar, P., Pawar, H., Sahasrabhuddhe, N.A., Suja, M.S., Ramachandra, Y.L., Prasad, T.S., Madhusudhana, S.N., Hc, H., Chaerkady, R., Satishchandra, P., Pandey, A., Shankar, S.K. (2013). ). Quantitative proteomics for identifying biomarkers for Rabies. . Clinical Proteomics. 10(1):001-13. [PubMed]

Marimuthu, A., Subbannayya, Y., Sahasrabuddhe, N. A., Balakrishnan, L., Syed, N., Sekhar, N. R., Katte, T. V., Pinto, S. M., Srikanth, S. M., Kumar, P., Pawar, H., Kashyap, M. K., Maharudraiah, J., Ashktorab, H., Smoot, D. T., Ramaswamy, G., Kumar, R. V., Cheng, Y., Meltzer, S. J., Roa, J. C., Chaerkady, R., Prasad, T. S. K., Harsha, H. C., Chatterjee, A. and Pandey, A. (2013). SILAC-based quantitative proteomic analysis of gastric cancer secretome.. Proteomics - Clinical Applications. 7(005-6):355-66. [PubMed]

Kashyap, M. K., Pawar, H., Keerthikumar, S., Sharma, J., Goel, R., Mahmood, R., Vijaya Kumar, M., Veerendra Kumar, K. V., Pandey, A., Kumar, R. V., Prasad, T. S. K. and Harsha, H. C. (2012). "Evaluation of protein expression pattern of stanniocalcin 2, insulin-like growth factor-binding protein 7, inhibin beta A and four and a half LIM domains 1 in esophageal squamous cell carcinoma. ". Cancer Biomarkers. 12(1):001-9. [PubMed]

Pawar, H., Maharudraiah, J., Kashyap, M. K., Sharma, J., Srikanth, M. S., Choudhary, R., Chavan, S., Sathe, G., Manju, H.C., Veerendra Kumar, K. V., Vijayakumar, M., Sirdeshmukh, R., Harsha, H. C., Prasad, T. S. K., Pandey, A. and Kumar, R. V. (2012). Downregulation of cornulin in esophageal squamous cell carcinoma. Acta Histochemica 115(2):89-99. [PubMed]

Kumar, G.S.S., Venugopal, A.K., Mahadevan, A., Renuse, S., Harsha, H.C., Sahasrabuddhe, N.A., Pawar, H., Sharma, R., Kumar, P., Rajagopalan, S., Waddell, K., Ramachandra, Y.L., Satishchandra, P., Chaerkady, R., Prasad, T. S. K., Shankar, S. K. and Pandey, A. (2012). Quantitative proteomics for identifying biomarkers for tuberculous meningitis. Clinical Proteomics 9(1):001-13. [PubMed]

Telikicherla, D., Maharudraiah, J., Pawar, H., Marimuthu, A., Kashyap, M. K., Ramachandra, Y. L., Roa, J. C. and Pandey, A. (2012). Overexpression of Kinesin Associated Protein 3 (KIFAP3) in Breast Cancer. Journal of Proteomics and Bioinformatics. Journal of Proteomics and Bioinformatics 5(5):122-26. [PubMed]

Pawar, H., Sahasrabuddhe, N. A., Renuse, S., Keerthikumar, S., Sharma, J., Kumar, G. S. S., Venugopal, A., Sekhar, N. R., Kelkar, D. S., Nemade, H., Khobragade, S. N., Muthusamy, B., Kandasamy, K., Harsha, H. C., Chaerkady, R., Patole, M. S. and Pandey, A. (2012). A proteogenomic analysis of Anopheles gambiae using high-resolution Fourier transform mass spectrometry. Proteomics 12(6):832-44. [PubMed]

Chaerkady, R., Kelkar, D. S., Muthusamy, B., Kandasamy, K., Dwivedi, S. B., Sahasrabuddhe, N. A., Kim, M-S., Renuse, S., Pinto, S. M., Sharma, R., Pawar, H., Sekhar, N. R., Mohanty, A. K., Getnet, D., Yang, Y., Zhong, J., Dash, A. P., MacCallum, R. M., Delanghe, B., Mlambo, G., Kumar, A., Prasad, T. S. K., Okulate, M., Kumar, N. and Pandey, A. (2011). A proteogenomic analysis of Anopheles gambiae using high-resolution Fourier transform mass spectrometry. Genome Research 21(11):1872-81. [PubMed]

Pawar, H., Kashyap, M.K., Sahasrabuddhe, N.A., Renuse, S., Harsha, H.C., Kumar, P., Sharma, J., Kandasamy, K., Marimuthu, A., Nair, B., Rajagopalan, S., Maharudraiah, J., Premalatha, C.S., Veerendra Kumar, K.V., Vijayakumar, M., Chaerkady, R., Prasad, T.S.K., Kumar, R.V. and Pandey, A. (2011). Quantitative tissue proteomics of esophageal squamous cell carcinoma for novel biomarker discovery. Cancer Biology and Therapy. 12(6):510-22. [PubMed]

Kashyap, M.K., Harsha, H.C., Renuse, S., Pawar, H., Sahasrabuddhe, N.A., Kim, M.S., Marimuthu, A., Keerthikumar, S., Muthusamy, B., Kandasamy, K., Subbannayya, Y., Prasad, T.S.K., Mahmood, R., Chaerkady, R., Meltzer, S.J., Kumar, R.V., Rustgi, A.K. and Pandey, A. (2010). SILAC-based quantitative proteomic approach to identify potential biomarkers from the esophageal squamous cell carcinoma secretome. Cancer Biology and Therapy. 10(8):796-810. [PubMed]

Prasad, T.S.K., Keerthikumar, S., Chaerkady, R., Kandasamy, K., Renuse, S., Marimuthu, A., Venugopal, A.K., Thomas, J.K., Jacob, H.K.C., Goel, R., Pawar, H., Sahasrabuddhe, N.A., Krishna, V., Nair, B.G., Gucek, M., Cole, R.N., Ravikumar, R., Harsha, H.C. and Pandey, A. (2010). Comparative proteomic analysis of Candida albicans and Candida glabrata. Clinical Proteomics 6:163173. [PubMed]

Kandasamy, K., Keerthikumar, S., Goel, R., Mathivanan, S., Patankar, N., Shafreen, B., Renuse, S., Pawar, H., Ramachandra, Y. L., Acharya, P. K., Ranganathan, P., Chaerkady, R., Prasad, T.S.K. and Pandey, A. (2009). Human Proteinpedia: A unified discovery resource for proteomics research. Nucleic Acids Research. 37:D773-81. [PubMed]

Honors and Awards

Associate Fellow in Higher Education Academy (AFHEA), Lancaster University, United Kingdom 2024
Individual Staff Development Award awarded by Lancaster University 2023
Career Development Award Scheme awarded by Faculty of Health and Medicine (FHM), Lancaster University 2023
Planning and Budgeting Committee (PBC) Postdoctoral Fellowship (to pursue postdoctoral research at Faculty of Biology, Technion- Israel Institute of Technology, Haifa, Israel) July 2016 - December 2020
University Grants Commission (UGC) Dr. D. S. Kothari Postdoctoral Fellowship (to pursue postdoctoral research at Department of Zoology, Savitribai Phule Pune University, Pune, India) February 2015 - June 2016
Council of Scientific and Industrial Research (CSIR), Government of India sponsored Junior Research Fellowship to pursue PhD at Institute of Bioinformatics, Bangalore, India. July 2008 to June 2013

Memberships

Royal Society of Biology
British Society for Parasitology
The Royal Society of Tropical Medicine and Hygiene (RSTMH)
The Israel Society for Biochemistry and Molecular Biology (ISBMB)