Director
Publications
Molecular Biology Lab
Proteomics
Metabolomics
Infractructure
Phd
funding
Collaborators
visitors gallery
Trainees
 
Renu Pandey, Ph.D.
Faculty Scientist
 
Institute of Bioinformatics
Discoverer Building, International Tech Park, Whitefield
Bangalore - 560 066
E-mail: renupandey at ibioinformatics dot org
 
Education
Ph.D. in Analytical Chemistry, CSIR-Central Drug Research Institute, India
M.Sc. in Chemistry, Kumaun University, Nainital, India
 

Positions Held

Faculty Scientist, Institute of Bioinformatics, Bangalore, India, 2025-Present
Research Scientist, Indian Institute of Technology, Bombay, India, 2023-2025
Postdoctoral Fellow, Dell Medical School, The University of Texas at Austin, TX, USA, 2016-2019
Guest Lecturer, Department of Chemistry, Kumaun University, Nainital, India, 2010-2011
 

Area of Specialization

Metabolomics
Lipidomics
 

Publications

Research Articles: 30 [Google Scholar]


Pandey, R., Tiziani, S. (2024). Advances in Chiral Metabolomic Profiling and Biomarker Discovery. Methods in Molecular Biology 2855:85-101 [PubMed]

Balinda, H.U., Kelly, W. J., Kaklamani, V.G., Lathrop, K.I., Canola, M.M., Ghamasaee, P., Sareddy, G.R., Michalek, J., Gilbert, A.R., Surapaneni, P., Tiziani, S., Pandey, R., Chiou, J., Lodi, A., Floyd, J.R., Brenner, A.J. (2024). Sacituzumab Govitecan in patients with breast cancer brain metastases and recurrent glioblastoma: a phase 0 window-of-opportunity trial. Nature Communications 15(1):6707 [PubMed]

Lodi, A., Pandey, R., Chiou, J., Bhattacharya, A., Huang, S., Pan, X., Burgman, B., Yi, S.S., Tiziani, S., Brenner, A.J. (2022). Circulating metabolites associated with tumor hypoxia and early response to treatment in Bevacizumab-refractory glioblastoma after combined Bevacizumab and Evofosfamide. Frontiers in Oncology 12:900082 [PubMed]

Baran, N., Lodi, A., Dhungana, Y., Herbrich, S., Collins, M., Sweeney, S., Pandey, R., Skwarska, A., Patel, S., Tremblay, M., Kuruvilla, V.M., Cavazos, A., Kaplan, M., Warmoes, M.O., Veiga, D.T., Furudate, K., Sutterin, S. R., Haman, A., Gareau, Y., Marinier, A., Ma, H., Harutyunyan, K., Daher, M., Garcia, L.M., Al-Atrash, G., Piya, S., Ruvolo, V., Yang, W., Shanmugavelandy, S.S., Feng, N., Gay, J., Du, D., Yang, J.J., Hoff, F.W., Kaminski, M., Tomczak, K., Davis, R.E., Herranz, D., Ferrando, A., Jabbour, E.J., Francesco, M.E.D., Teachey, D.T., Horton, T. M., Kornblau, S., Rezvani, K., Sauvageau, G., Gagea, M., Andreeff, M., Takahashi, K., Marszalek, J.R., Lorenzi, P.L., Yu, J., Tiziani, S., Hoang, T., Konopleva, M. (2022). Inhibition of Mitochondrial complex I reverses the NOTCH1-driven metabolic reprogramming in T-ALL. Nature Communications 13(1):01-020 [PubMed]

Pandey, R., Collins, M., Lu, X., Sweeney, S.R., Chiou, J., Lodi, A., Tiziani, S. (2021). Novel Strategy for Untargeted Chiral Metabolomics using Liquid Chromatography-High Resolution Tandem Mass Spectrometry. Analytical chemistry 93(14):5805-5814 [PubMed]

Shukla, S., Pandey, R., Kumar, B., Tewari, S.K., Pal, M. (2021). Phenolic compounds and radical scavenging activity of Senna tora (L.) Roxb. herbs collected from various geographical locations of India. Pharmaceutical Chemistry Journal 55:684-690 [Article]

Pandey, R., Gruslova, A., Chiou, J., Brenner, A.J., Tiziani, S. (2020). "Stable Isotope Dilution LC-HRMS Assay to Determine Free SN-38, Total SN-38, and SN-38G in a Tumor Xenograft Model after Intravenous Administration of Antibody-Drug Conjugate ". Analytical chemistry 92(1):1260-1267 [PubMed]

Kosti, A., De Araujo, P.R., Li, W.Q., Guardia, G.D., Chiou, J., Yi, C., Ray, D., Meliso, F., Li, Y.M., Delambre, T., Qiao, M., Burns, S.S., Lorbeer, F.K., Georgi, F., Flosbach, M., Klinnert, S., Jennseit, A., Lei, X., Sandoval, C.R., Ha, K., Zheng, H., Pandey, R., Gruslova, A., Gupta, Y., Brenner, A., Kokovay, E., Hughes, T.R., Morris, Q.D., Galante, P.A.F., Tiziani, S., Penalva, L.O.F. (2020). The RNA binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging "cancer metabolism" and "epigenetic regulation". Genome Biology 21(1):01-032 [PubMed]

Lu, W.C., Saha, A., Yan, W., Garrison, K., Lamb, C., Pandey, R., Irani, S., Lodi, A., Lu, X., Tiziani, S., Zhang, Y.J. (2020). Enzyme-mediated depletion of serum l-Met abrogates prostate cancer growth via multiple mechanisms without evidence of systemic toxicity. Proceedings of the National Academy of Sciences of the United States of America 117(23):13000-13011 [PubMed]

Sweeney, S.R., Collins, M., Pandey, R., Chiou, J., Lodi, A., Tiziani, S. (2020). Identification of a synergistic combination of dimethylaminoparthenolide and shikonin alters metabolism and inhibits proliferation of pediatric precursor?B cell acute lymphoblastic leukemia. Molecular Carcinogenesis 59(4):399-411 [PubMed]

Pandey, R., Riley, C.L., Mills, E.M., Tiziani, S. (2018). Highly sensitive and selective determination of redox states of coenzymes Q 9 and Q 10 in mice tissues: Application of orbitrap mass spectrometry. Analytica Chimica Acta 1011:68-76 [PubMed]

Pandey, R., Caflisch, L., Lodi, A., Brenner, A.J. and Tiziani, S. (2017). Metabolomic signature of brain cancer. Molecular Carcinogenesis 56(11):2355-2371 [PubMed]

Pandey, R., Kumar, B., Meena, B., Srivastava, M., Mishra, T., Tiwari, V., Pal, M., Nair, N.K., Upreti, D.K., Rana, T.S. (2017). "Major bioactive phenolics in Bergenia species from the Indian Himalayan region: Method development, validation and quantitative estimation using UHPLC-QqQLIT-MS/MS,". PLOS One 12(7):e0180950 [PubMed]

Singh, D., Kumar, S., Pandey, R., Hasanain, M., Sarkar, J., Kumar, B. (2017). Bioguided chemical characterization of the antiproliferative fraction of edible pseudo bulbs of Malaxis acuminata D. Don by HPLC-ESI-QTOF-MS. Medicinal Chemistry Research 26(12):3307-3314 [Article]

Pandey, R., Mahar, R., Hasanain, M., Shukla, S.K., Sarkar, J., Rameshkumar, K.B., Kumar, B. (2016). Rapid screening and quantitative determination of bioactive compounds from fruit extracts of Myristica species and their in vitro antiproliferative activity. Food Chemistry 211:483-493 [PubMed]

Pandey, R., Chandra, P., Kumar, B., Dutt, B., Sharma, K.R. (2016). A rapid and highly sensitive method for simultaneous determination of bioactive constituents in leaf extracts of six Ocimum species using ultra high performance liquid chromatography-hybrid linear ion trap triple quadrupole mass spectrometry. Analytical Methods 8(2):333-341 [Article]

"Chandra, P., Kannujia, R., Pandey, R., Shukla, S., Bahadur, L., Pal, M., Kumar, B." (2016). Rapid quantitative analysis of multi-components in Andrographis paniculata using UPLC-QqQLIT-MS/MS: Application to soil sodicity and organic farming. Industrial Crops and Products 83:423-430 [Article]

Pandey, R., Kumar, B. (2016). HPLC-QTOF-MS/MS based rapid screening of phenolics and triterpenic acids in leaf extracts of Ocimum species and their interspecies variation. Journal of Liquid Chromatography & Related Technologies 39(4):225-238 [Article]

Aravind, A.P.A., Pandey, R., Kumar, B., Asha, K.R., Rameshkumar, K.B. (2016). Phytochemical Screening of Garcinia travancorica by HPLC-ESI-QTOF Mass Spectrometry and Cytotoxicity Studies of the Major Biflavonoid Fukugiside. Natural Product Communications 11(12):1839-1842 [PubMed]

Pandey, R., Rameshkumar, K.B., Kumar, B. (2015). Ultra high performance liquid chromatography tandem mass spectrometry method for the simultaneous determination of multiple bioactive constituents in fruit extracts of Myristica fragrans and its marketed polyherbal formulations using a polarity switching technique. Journal of Separation Science 38(8):277-1285 [PubMed]

Pandey, R., Chandra, P., Kumar, B., Srivastva, M., Aravind, A.A., Shameer, P.S., Rameshkumar, K.B. (2015). Simultaneous determination of multi-class bioactive constituents for quality assessment of Garcinia species using UHPLC-QqQLIT-MS/MS. Industrial Crops and Products 77:861-872 [Article]

Pandey, R., Chandra, P., Srivastava, M., Mishra, D.K. and Kumar, B. (2015). Simultaneous quantitative determination of multiple bioactive markers in Ocimum sanctum obtained from different locations and its marketed herbal formulations using UPLC-ESI-MS/MS combined with principal component analysis. Phytochemical Analysis 26(6):383-394 [PubMed]

Chandra, P., Pandey, R., Kumar, B., Srivastva, M., Pandey, P., Sarkar, J. and Singh, B.P. (2015). Quantification of multianalyte by UPLC-QqQLIT-MS/MS and in-vitro anti-proliferative screening in Cassia species. Industrial Crops and Products 76:1133-1141 [Article]

Chandra, P., Pandey, R., Srivastva, M., Rameshkumar, K.B. and Kumar, B. (2015). "Quantitative determination of chemical constituents of Piper spp. using UPLC-ESI-MS/MS, ". Industrial Crops and Products 76:967-976 [Article]

Chandra, P., Pandey, R., Srivastva, M., Kumar, B. (2015). Quality control assessment of polyherbal formulation based on a quantitative determination multimarker approach by ultra high performance liquid chromatography with tandem mass spectrometry using polarity switching combined with multivariate analysis. Journal of Separation Science 38(18):3183-3191 [PubMed]

Pandey, R., Chandra, P., Arya, K.R., Kumar, B. (2014). Development and validation of an ultra-high-performance liquid chromatography electrospray ionization tandem mass spectrometry method for the simultaneous determination of selected flavonoids in Ginkgo biloba. Journal of Separation Science 37(24):3610-3618 [PubMed]

Pandey, R., Chandra, P., Srivastva, M., Arya, K.R., Shukla, P.K. and Kumar, B. (2014). A rapid analytical method for characterization and simultaneous quantitative determination of phytoconstituents in Piper betle landraces using UPLC-ESI-MS/MS. Analytical Methods 6(18):7349-7360. [Article]

Bajpai, V., Pandey, R., Negi, M.P.S., Kumar, N. and Kumar, B. (2013). A strategy to access fused triazoloquinoline and related nucleoside analogues. Tetrahedron 69(40):8547-8558 [Article]

Bajpai, V., Pandey, R., Negi, M.P.S., Kumar, N. and Kumar, B. (2013). DART MS Based chemical profiling for therapeutic potential of Piper betle landraces. Natural Product Communications 7(10):1627-1630 [PubMed]

Bajpai, V., Pandey, R., Negi, M.P.S., Bindu, K.H., Kumar, N. and Kumar, B. (2012). Characteristic differences in metabolite profile in male and female plants of dioecious Piper betle L. Journal of Biosciences 37(1):1061-1066 [PubMed]

 

Research Support

  Title of Project   Funding Agency   Role
1 A comprehensive biochemical and metabolomic approach to identify and classify variants underlying lysosomal storage disorders in Indian patients Indian Council of Medical Research, New Delhi Co-PI
 
Honors and Awards
CMCT Travel Award by Center for Molecular Carcinogenesis and Toxicology, The University of Texas at Austin, Texas, USA. 2018
Postdoctoral Fellowship awarded by The University of Texas at Austin, Texas, USA. 2016
Best Poster Prize at the "National Seminar on Applications of Mass and NMR Techniques in Drug Research" awarded by CSIR-Central Drug Research Institute, Lucknow, UP, India. 2014
International Travel Fellowship awarded by SERB, Department of Science & Technology, India. 2014
CSIR/UGC NET Senior Research Fellowship awarded by Council of Scientific and Industrial Research, New Delhi, India. 2013-2016
CSIR/UGC NET Junior Research Fellowship awarded by Council of Scientific and Industrial Research, New Delhi, India. 2011-2013
M. Sc. Gold medal (1st rank in the University for the course M. Sc. Chemistry) awarded by Kumaun University, Nainital, Uttarakhand, India. 2010